TULP3 rabbit pAb

    • 货号:YT7270
    • 应用:WB
    • 种属:Human;Mouse
      • 靶点:
      • TULP3
      • 基因名称:
      • TULP3 TUBL3
      • 蛋白名称:
      • TULP3
      • Human Gene Id:
      • 7289
      • Human Swiss Prot No:
      • O75386
      • Mouse Swiss Prot No:
      • O88413
      • 免疫原:
      • Synthesized peptide derived from human TULP3 AA range: 257-307
      • 特异性:
      • This antibody detects endogenous levels of TULP3 at Human/Mouse
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 49kD
      • 背景:
      • This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2009],
      • 功能:
      • similarity:Belongs to the TUB family.,tissue specificity:Expressed at high levels in testis, ovaries, thyroid, and spinal chord.,
      • 细胞定位:
      • Nucleus. Cell membrane. Cell projection, cilium . Cytoplasm . Secreted . Does not have a cleavable signal peptide and is secreted by a non-conventional pathway (By similarity). Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha. .
      • 组织表达:
      • Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
      • 产品图片
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night