• 靶点：
• ZMYM3

• 基因名称：
• ZMYM3 DXS6673E KIAA0385 ZNF261

• 蛋白名称：
• ZMYM3

• Human Gene Id：
• 9203

• Human Swiss Prot No：
• Q14202

• Mouse Gene Id：
• 56364

• Mouse Swiss Prot No：
• Q9JLM4

• 免疫原：
• Synthesized peptide derived from human ZMYM3 AA range: 258-308

• 特异性：
• This antibody detects endogenous levels of ZMYM3 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 151kD

• 背景：
• This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010],

• 功能：
• disease:A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).,similarity:Contains 9 MYM-type zinc fingers.,subunit:May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I.,tissue specificity:Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.

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