TCEA1 rabbit pAb

    • 货号:YT7143
    • 应用:WB
    • 种属:Human;Mouse;Rat
      • 靶点:
      • TCEA1
      • 基因名称:
      • TCEA1 GTF2S TFIIS
      • 蛋白名称:
      • TCEA1
      • Human Gene Id:
      • 6917
      • Human Swiss Prot No:
      • P23193
      • Mouse Swiss Prot No:
      • P10711
      • 免疫原:
      • Synthesized peptide derived from human TCEA1 AA range: 50-100
      • 特异性:
      • This antibody detects endogenous levels of TCEA1 at Human/Mouse/Rat
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 33kD
      • 功能:
      • alternative products:Additional isoforms seem to exist,disease:A chromosomal rearrangement involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1.,function:Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.,miscellaneous:S-II binds to RNA-polymerase II in the absence of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TFS-II family.,similarity:Contains 1 TFIIS
      • 细胞定位:
      • Nucleus.
      • 产品图片
      • Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night