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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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SAC2 rabbit pAb
- 货号:YT7095
- 应用:WB
- 种属:Human;Mouse
- 简介:
- >>Inositol phosphate metabolism;>>Metabolic pathways;>>Phosphatidylinositol signaling system
- 基因名称:
- INPP5F KIAA0966 SAC2 MSTP007 MSTP047
- 免疫原:
- Synthesized peptide derived from human SAC2 AA range: 1006-1056
- 特异性:
- This antibody detects endogenous levels of SAC2 at Human/Mouse
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景:
- The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],
- 功能:
- function:Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-triphosphate. Hydrolyzes phosphatidylinositol 4,5-bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation.,miscellaneous:Inositol polyphosphate 5-phosphatases usually have 2 conserved motifs that are essential for 5-phosphatase activity. However, INPP5F does not contain such motifs, and phosphatase activity seems to exist in the SAC domain, suggesting a new type of phosphoinositide 5-phosphatase.,similarity:Contains 1 SAC domain.,tissue specificity:Ubiquitous.,
- 细胞定位:
- Membrane, clathrin-coated pit . Early endosome . Recycling endosome . Also found on macropinosomes. .
- 组织表达:
- Ubiquitous (PubMed:11274189). Highly expressed in brain (PubMed:26203138).
![](/uploadfiles/PIC/YT7095wb-2019.jpg)
- Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night