DEN1A rabbit pAb

    • 货号：YT7090
    • 应用：WB
    • 种属：Human;Mouse
      • 靶点：
      • DEN1A
      • 基因名称：
      • DENND1A FAM31A KIAA1608
      • 蛋白名称：
      • DEN1A
      • Human Swiss Prot No：
      • Q8TEH3
      • Mouse Swiss Prot No：
      • Q8K382
      • 免疫原：
      • Synthesized peptide derived from human DEN1A AA range: 14-64
      • 特异性：
      • This antibody detects endogenous levels of DEN1A at Human/Mouse
      • 组成：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源：
      • Polyclonal, Rabbit,IgG
      • 稀释：
      • WB 1：500-2000
      • 纯化工艺：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度：
      • 1 mg/ml
      • 储存：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量：
      • 111kD
      • 背景：
      • Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010],
      • 功能：
      • function:May be involved in the clathrin-mediated endocytosis of synaptic vesicles.,similarity:Contains 1 dDENN domain.,similarity:Contains 1 DENN domain.,similarity:Contains 1 uDENN domain.,subunit:Interacts with AP2B1, ITSN1 AND SH3GL2.,
      • 细胞定位：
      • Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein . Cell junction, synapse, presynaptic cell membrane . Associates to membranes via lipid-binding activity. .
      • 产品图片
      • Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night

      相关报价

      • 货号：
      • YT7090
      • 规格：
      • 40μL / 100μL / 200μL
      • 价格：
      • ¥960 / 2300 / 3780
      • 货期：
      • 预计发货时间为
        2024-09-03
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