• 靶点：
• DET1

• 简介：
• >>Ubiquitin mediated proteolysis

• 基因名称：
• DET1

• 蛋白名称：
• DET1

• Human Gene Id：
• 55070

• Human Swiss Prot No：
• Q7L5Y6

• Mouse Gene Id：
• 76375

• Mouse Swiss Prot No：
• Q9D0A0

• 免疫原：
• Synthesized peptide derived from human DET1 AA range: 48-98

• 特异性：
• This antibody detects endogenous levels of DET1 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 61kD

• 功能：
• function:Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.,similarity:Belongs to the DET1 family.,subunit:Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1, DET1, DDB1, CUL4A and COP1.,tissue specificity:Highly expressed in the ovary, some lymphoid organs and resting leukocytes.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Highly expressed in the ovary, some lymphoid organs and resting leukocytes.

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