• 靶点：
• CDC26

• 简介：
• >>Cell cycle;>>Oocyte meiosis;>>Ubiquitin mediated proteolysis;>>Progesterone-mediated oocyte maturation;>>Human T-cell leukemia virus 1 infection

• 基因名称：
• CDC26 ANAPC12 C9orf17

• 蛋白名称：
• CDC26

• Human Gene Id：
• 246184

• Human Swiss Prot No：
• Q8NHZ8

• Mouse Gene Id：
• 66440

• Mouse Swiss Prot No：
• Q99JP4

• Rat Gene Id：
• 366381

• Rat Swiss Prot No：
• Q6YDN7

• 免疫原：
• Synthesized peptide derived from human CDC26 AA range: 21-71

• 特异性：
• This antibody detects endogenous levels of CDC26 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1：50-200. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 9kD

• 背景：
• The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various proteins. [provided by RefSeq, Jul 2008],

• 功能：
• function:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase that controls progression through mitosis and the G1 phase of the cell cycle. May recruit the E2 ubiquitin-conjugating enzymes to the complex.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CDC26 family.,subunit:The APC/C is composed of at least 11 subunits.,

• 细胞定位：
• Nucleus .

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