• 靶点：
• TBCD7

• 简介：
• >>mTOR signaling pathway

• 基因名称：
• TBC1D7 HSPC239 TBC7

• 蛋白名称：
• TBCD7

• Human Gene Id：
• 51256

• Human Swiss Prot No：
• Q9P0N9

• Mouse Gene Id：
• 67046

• Mouse Swiss Prot No：
• Q9D0K0

• 免疫原：
• Synthesized peptide derived from human TBCD7 AA range: 85-135

• 特异性：
• This antibody detects endogenous levels of TBCD7 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 32kD

• 背景：
• This gene encodes a member of the TBC-domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1-TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus and downstream LOC100130357. [provided by RefSeq, Jan 2016],

• 功能：
• function:May act as a GTPase-activating protein for Rab family protein(s) .,similarity:Contains 1 Rab-GAP TBC domain.,

• 细胞定位：
• Cytoplasmic vesicle . Localizes in the cytoplasmic vesicles of the endomembrane in association with TSC1-TSC2 complex.

• 组织表达：
• Highly expressed in heart, and slightly in kidney, liver and placenta.

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