TXND8 rabbit pAb

    • 货号:YT6952
    • 应用:WB
    • 种属:Human;Mouse;Rat
      • 靶点:
      • TXND8
      • 基因名称:
      • TXNDC8 SPTRX3 TRX6
      • 蛋白名称:
      • TXND8
      • Human Swiss Prot No:
      • Q6A555
      • Mouse Swiss Prot No:
      • Q69AB2
      • 免疫原:
      • Synthesized peptide derived from human TXND8 AA range: 64-114
      • 特异性:
      • This antibody detects endogenous levels of TXND8 at Human/Mouse/Rat
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 14kD
      • 功能:
      • function:May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.,miscellaneous:Increased levels, possibly caused by overexpression, are observed in morphologically abnormal spermatozoa from infertile men, suggesting that it may be used as a marker of aberrant spermatogenesis.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).,
      • 细胞定位:
      • Cytoplasm . Golgi apparatus .
      • 组织表达:
      • Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level).
      • 产品图片
      • Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night