ZRAN1 rabbit pAb

    • 货号:YT6929
    • 应用:WB
    • 种属:Human;Mouse
      • 靶点:
      • ZRAN1
      • 基因名称:
      • ZRANB1 TRABID
      • 蛋白名称:
      • ZRAN1
      • Human Swiss Prot No:
      • Q9UGI0
      • Mouse Swiss Prot No:
      • Q7M760
      • 免疫原:
      • Synthesized peptide derived from human ZRAN1 AA range: 255-305
      • 特异性:
      • This antibody detects endogenous levels of ZRAN1 at Human/Mouse
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 78kD
      • 功能:
      • domain:The OTU domain mediates the deubiquitinating activity.,domain:The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.,function:Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.,similarity:Belongs to the peptidase C64 family.,similarity:Contains 1 OTU domain.,similarity:Contains 3 RanBP2-type zinc fingers.,subunit:Interacts with APC and TRAF6.,tissue specificity:Widely expressed.,
      • 细胞定位:
      • Cytoplasm . Nucleus . Enriched in punctate localization in the cytoplasm. .
      • 组织表达:
      • Widely expressed.
      • 产品图片
      • Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night