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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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C1GLT rabbit pAb
- 货号:YT6838
- 应用:WB
- 种属:Human;Mouse;Rat
- 简介:
- >>Mucin type O-glycan biosynthesis;>>Other types of O-glycan biosynthesis;>>Metabolic pathways
- 免疫原:
- Synthesized peptide derived from human C1GLT AA range: 102-152
- 特异性:
- This antibody detects endogenous levels of C1GLT at Human/Mouse/Rat
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景:
- The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010],
- 功能:
- catalytic activity:UDP-galactose + glycoprotein N-acetyl-D-galactosamine = UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine.,cofactor:Magnesium.,disease:Defects in C1GALT1 may be a cause of susceptibility to IgA nephropathy (IgAN). IgAN is the most common primary glomerulonephritis, which is partly due to aberrant or incomplete galactosylation of IgA1 molecules.,function:Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.,online information:Core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.,
- 细胞定位:
- Membrane ; Single-pass type II membrane protein .
- 组织表达:
- Widely expressed. Highly expressed in kidney, heart, placenta and liver.
![](/uploadfiles/PIC/YT6838wb-2019.jpg)
- Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night