• 靶点：
• DDAH1

• 基因名称：
• DDAH1 DDAH

• 蛋白名称：
• DDAH1

• Human Gene Id：
• 23576

• Human Swiss Prot No：
• O94760

• Mouse Gene Id：
• 69219

• Mouse Swiss Prot No：
• Q9CWS0

• Rat Gene Id：
• 64157

• Rat Swiss Prot No：
• O08557

• 免疫原：
• Synthesized peptide derived from human DDAH1 AA range: 115-165

• 特异性：
• This antibody detects endogenous levels of DDAH1 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 31kD

• 背景：
• This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008],

• 功能：
• catalytic activity:N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.,cofactor:Binds 1 zinc ion.,function:Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in nitric oxide generation.,similarity:Belongs to the DDAH family.,subunit:Monomer.,

• 细胞定位：
• mitochondrion,cytosol,extracellular exosome,

• 组织表达：
• Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.

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