- 靶点:
- BT3A3
- 基因名称:
- BTN3A3 BTF3
- 蛋白名称:
- BT3A3
- Human Gene Id:
- 10384
- Human Swiss Prot No:
- O00478
- 免疫原:
- Synthesized peptide derived from human BT3A3 AA range: 148-198
- 特异性:
- This antibody detects endogenous levels of BT3A3 at Human
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 分子量:
- 64kD
- 背景:
- The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010],
- 功能:
- similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,
- 细胞定位:
- Cell membrane ; Single-pass type I membrane protein .
- 组织表达:
- Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes.
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- 产品图片
- Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night