F8I2 rabbit pAb

    • 货号：YT6594
    • 应用：WB
    • 种属：Human;Mouse
      • 靶点：
      • F8I2
      • 基因名称：
      • F8A1 F8A; F8A2 F8A; F8A3 F8A
      • 蛋白名称：
      • F8I2
      • Human Swiss Prot No：
      • P23610
      • Mouse Swiss Prot No：
      • Q00558
      • 免疫原：
      • Synthesized peptide derived from human F8I2 AA range: 33-83
      • 特异性：
      • This antibody detects endogenous levels of F8I2 at Human/Mouse
      • 组成：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源：
      • Polyclonal, Rabbit,IgG
      • 稀释：
      • WB 1：500-2000
      • 纯化工艺：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度：
      • 1 mg/ml
      • 储存：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量：
      • 41kD
      • 背景：
      • This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb, and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h), containing F8A, is repeated twice extragenically closer to the Xq telomere. Although its function is unknown, the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types. [provided by RefSeq, Jul 2008],
      • 功能：
      • function:Not known. Possible housekeeping role.,tissue specificity:Produced abundantly in a wide variety of cell types.,
      • 细胞定位：
      • Cytoplasm . Nucleus . Early endosome . Nucleus, nuclear body . Diffuse presence in the cytoplasm and accumulation in the nucleus (PubMed:16476778). In absence of HTT, F8A1/F8A2/F8A3 is concentred in cytoplasm (By similarity). Colocalized with HTT in endosomes (PubMed:16476778). In neuron found in intranuclear structures, the intranuclear rodlets (INRs), also known as rodlets of Roncoroni, in association with ubiquitin (By similarity). .
      • 组织表达：
      • Produced abundantly in a wide variety of cell types.
      • 产品图片
      • Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night

      相关报价

      • 货号：
      • YT6594
      • 规格：
      • 40μL / 100μL / 200μL
      • 价格：
      • ¥960 / 2300 / 3780
      • 货期：
      • 预计发货时间为
        2024-09-04
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