• 靶点：
• GLDN

• 基因名称：
• GLDN COLM UNQ9339/PRO34011

• 蛋白名称：
• GLDN

• Human Gene Id：
• 342035

• Human Swiss Prot No：
• Q6ZMI3

• Mouse Gene Id：
• 235379

• Mouse Swiss Prot No：
• Q8BMF8

• Rat Gene Id：
• 315675

• Rat Swiss Prot No：
• Q80WL1

• 免疫原：
• Synthesized peptide derived from human GLDN AA range: 461-511

• 特异性：
• This antibody detects endogenous levels of GLDN at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 61kD

• 功能：
• domain:The olfactomedin-like domain mediates NFASC/neurofascin and NRCAM binding.,function:Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier.,similarity:Contains 1 olfactomedin-like domain.,similarity:Contains 2 collagen-like domains.,subcellular location:Localizes to the nodes of Ranvier.,subunit:Interacts with NFASC/neurofascin and NRCAM.,tissue specificity:Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.,

• 细胞定位：
• Cell membrane ; Single-pass type II membrane protein . Cell projection, axon . Detected at the nodes of Ranvier. Detected at immature heminodes. .; [Gliomedin shedded ectodomain]: Secreted . Secreted, extracellular space, extracellular matrix . Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier. .

• 组织表达：
• Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system.

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