• 靶点：
• ATD3A

• 基因名称：
• ATAD3A

• 蛋白名称：
• ATD3A

• Human Gene Id：
• 55210

• Human Swiss Prot No：
• Q9NVI7

• 免疫原：
• Synthesized peptide derived from human ATD3A AA range: 433-483

• 特异性：
• This antibody detects endogenous levels of ATD3A at Human

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 70kD

• 背景：
• ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008],

• 功能：
• similarity:Belongs to the AAA ATPase family.,

• 细胞定位：
• Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion matrix, mitochondrion nucleoid . In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane (PubMed:20349121, PubMed:20154147). The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (PubMed:18063578). .

• 组织表达：
• Overexpressed in lung adenocarcinomas (at protein level).

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