LRC3B rabbit pAb

    • 货号:YT6501
    • 应用:WB;IHC
    • 种属:Human;Mouse
      • 靶点:
      • LRC3B
      • 基因名称:
      • LRRC3B LRP15 UNQ195/PRO221
      • 蛋白名称:
      • LRC3B
      • Human Swiss Prot No:
      • Q96PB8
      • Mouse Swiss Prot No:
      • Q8VCH9
      • 免疫原:
      • Synthesized peptide derived from human LRC3B AA range: 115-165
      • 特异性:
      • This antibody detects endogenous levels of LRC3B at Human/Mouse
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 28kD
      • 背景:
      • The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015],
      • 功能:
      • similarity:Belongs to the LRRC3 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,
      • 细胞定位:
      • Membrane ; Single-pass membrane protein .
      • 产品图片
      • Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).