• 靶点：
• ASTL

• 基因名称：
• ASTL

• 蛋白名称：
• ASTL

• Human Gene Id：
• 431705

• Human Swiss Prot No：
• Q6HA08

• Mouse Gene Id：
• 215095

• Mouse Swiss Prot No：
• Q6HA09

• 免疫原：
• Synthesized peptide derived from human ASTL AA range: 115-165

• 特异性：
• This antibody detects endogenous levels of ASTL at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 47kD

• 功能：
• enzyme regulation:Inhibited by wide spectrum metalloproteinase inhibitor batimastat (BB-94). Also inhibited by EDTA.,similarity:Belongs to the peptidase M12A family.,tissue specificity:Expressed in promyelocytic leukemia HL-60 cells, Burkitt's lymphoma Raji cells, and also in some ovarian carcinomas. Not detected in normal tissues.,

• 细胞定位：
• Cytoplasm . Cell membrane . Cytoplasmic vesicle, secretory vesicle, Cortical granule . Probably exocytosed from cortical granules during post-fertilization. Detected throughout the ooplasm of germinal vesicle stage oocytes in early bilaminar secondary follicles at postnatal (PN) day 3. Detected in the microvillar domain of the oolemma in arrested ovulated secondary oocytes and in the first polar body prior to fertilization. Upon fertilization, detected in the perivitelline space (PVS) and occasionally on the oolemma in 2-cell through morulae stages. Colocalizes with SPACA3 at the microvillar domain of the oolemma and in the perivitelline space (PVS). .

• 组织表达：
• Expressed in promyelocytic leukemia HL-60 cells, Burkitt's lymphoma Raji cells, and also in some ovarian carcinomas. Not detected in normal tissues.

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