• 靶点：
• ZN274

• 简介：
• >>Neurotrophin signaling pathway

• 基因名称：
• ZNF274 ZKSCAN19 SP2114

• 蛋白名称：
• ZN274

• Human Gene Id：
• 10782

• Human Swiss Prot No：
• Q96GC6

• 免疫原：
• Synthesized peptide derived from human ZN274 AA range: 111-161

• 特异性：
• This antibody detects endogenous levels of ZN274 at Human

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 72kD

• 背景：
• This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008],

• 功能：
• alternative products:Experimental confirmation may be lacking for some isoforms,function:Seems to function as a transcriptional repressor.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 2 KRAB domains.,similarity:Contains 5 C2H2-type zinc fingers.,

• 细胞定位：
• Cytoplasm . Nucleus, nucleolus .

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