• 靶点：
• HDA11

• 简介：
• >>Neutrophil extracellular trap formation;>>Alcoholism;>>Viral carcinogenesis

• 基因名称：
• HDAC11

• 蛋白名称：
• HDA11

• Human Gene Id：
• 79885

• Human Swiss Prot No：
• Q96DB2

• Mouse Gene Id：
• 232232

• Mouse Swiss Prot No：
• Q91WA3

• 免疫原：
• Synthesized peptide derived from human HDA11 AA range: 170-220

• 特异性：
• This antibody detects endogenous levels of HDA11 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 38kD

• 背景：
• This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009],

• 功能：
• catalytic activity:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.,function:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.,miscellaneous:Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.,sequence caution:Translated as Gln.,similarity:Belongs to the histone deacetylase family.,subcellular location:Predominantly nuclear.,subunit:Interacts with HDAC6.,tissue specificity:Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.

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