• 靶点：
• T2H2L

• 简介：
• >>Basal transcription factors;>>Nucleotide excision repair;>>Viral carcinogenesis

• 基因名称：
• GTF2H2C; GTF2H2D

• 蛋白名称：
• T2H2L

• Human Gene Id：
• 728340

• Human Swiss Prot No：
• Q6P1K8

• 免疫原：
• Synthesized peptide derived from human T2H2L AA range: 275-325

• 特异性：
• This antibody detects endogenous levels of T2H2L at Human

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 43kD

• 功能：
• alternative products:A number of isoforms may be produced. The isoforms may be also produced by incomplete gene duplication,function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.,similarity:Belongs to the GTF2H2 family.,similarity:Contains 1 VWFA domain.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with XPB, XPD, GTF2H1 and GTF2H3.,tissue specificity:Widely expressed, with higher express

• 细胞定位：
• Nucleus .

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