• 靶点：
• MD12L

• 简介：
• >>Thyroid hormone signaling pathway

• 基因名称：
• MED12L KIAA1635 TNRC11L TRALP TRALPUSH PRO0314

• 蛋白名称：
• MD12L

• Human Gene Id：
• 116931

• Human Swiss Prot No：
• Q86YW9

• Mouse Gene Id：
• 329650

• Mouse Swiss Prot No：
• Q8BQM9

• 免疫原：
• Synthesized peptide derived from human MD12L AA range: 1848-1898

• 特异性：
• This antibody detects endogenous levels of MD12L at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 236kD

• 背景：
• The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010],

• 功能：
• function:May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.,sequence caution:Contaminating sequence. Sequence of unknown origin in the N-terminal part and potential poly-A sequence.,similarity:Belongs to the Mediator complex subunit 12 family.,subunit:May be a component of the Mediator complex, which is known to be composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, ME

• 细胞定位：
• Nucleus .

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