• 靶点：
• S23A1

• 简介：
• >>Vitamin digestion and absorption

• 基因名称：
• SLC23A1 SVCT1 YSPL3

• 蛋白名称：
• S23A1

• Human Gene Id：
• 9963

• Human Swiss Prot No：
• Q9UHI7

• Mouse Gene Id：
• 20522

• Mouse Swiss Prot No：
• Q9Z2J0

• Rat Gene Id：
• 50621

• Rat Swiss Prot No：
• Q9WTW7

• 免疫原：
• Synthesized peptide derived from human S23A1 AA range: 237-287

• 特异性：
• This antibody detects endogenous levels of S23A1 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 66kD

• 背景：
• The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],

• 功能：
• alternative products:Experimental confirmation may be lacking for some isoforms,function:Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.,miscellaneous:Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells.,PTM:Phosphorylated.,similarity:Belongs to the xanthine/uracil permease family. SLC23A subfamily.,tissue specificity:Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein .

• 组织表达：
• Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.

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