• 靶点：
• APBB3

• 基因名称：
• APBB3 FE65L2

• 蛋白名称：
• APBB3

• Human Gene Id：
• 10307

• Human Swiss Prot No：
• O95704

• Mouse Gene Id：
• 225372

• Mouse Swiss Prot No：
• Q8R1C9

• Rat Gene Id：
• 117026

• Rat Swiss Prot No：
• O35827

• 免疫原：
• Synthesized peptide derived from human APBB3 AA range: 403-453

• 特异性：
• This antibody detects endogenous levels of APBB3 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 53kD

• 背景：
• The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• 功能：
• function:May modulate the internalization of beta-amyloid precursor protein.,similarity:Contains 1 WW domain.,similarity:Contains 2 PID domains.,subunit:Binds to the intracellular domain of the beta-amyloid precursor protein. Also bind to APP-like proteins.,tissue specificity:Expressed in various tissues.,

• 细胞定位：
• Cytoplasm . Nucleus .; [Isoform I-214]: Nucleus.; [Isoform I-245]: Nucleus.

• 组织表达：
• Expressed in various tissues, highest expression in brain.

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