• 靶点：
• BRD1

• 基因名称：
• BRD1 BRL BRPF2

• 蛋白名称：
• BRD1

• Human Gene Id：
• 23774

• Human Swiss Prot No：
• O95696

• 免疫原：
• Synthesized peptide derived from human BRD1 AA range: 399-449

• 特异性：
• This antibody detects endogenous levels of BRD1 at Human

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 116kD

• 背景：
• This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

• 功能：
• function:Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.,similarity:Contains 1 bromo domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Component of the MOZ/MORF composed at least of ING5, MYST3/MOZ, MYST4/MORF and one of BRPF1, BRD1/BRPF2 and BRPF3.,tissue specificity:Highly expressed in testis.,

• 细胞定位：
• Nucleus . Chromosome . Localizes to transcription start sites. .

• 组织表达：
• Highly expressed in testis.

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