Beta-defensin 1 Polyclonal Antibody
- 货号：YT6275
- 应用：IHC;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>ABC transporters;>>Staphylococcus aureus infection
- 免疫原：
- Synthesized peptide derived from human Beta-defensin 1 AA range: 1-50
- 特异性：
- This antibody detects endogenous levels of human Beta-defensin 1
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:50-200, ELISA(peptide)1:5000-20000
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Beta-defensin 1 (BD-1;hBD-1;Defensin, beta 1)
- 背景：
- Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008],
- 功能：
- function:Has bactericidal activity.,mass spectrometry: PubMed:7628632,similarity:Belongs to the beta-defensin family.,tissue specificity:Plasma.,
- 细胞定位：
- Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203). .
- 组织表达：
- Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level).
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
