• 靶点：
• CGT

• 简介：
• >>Ether lipid metabolism;>>Sphingolipid metabolism;>>Metabolic pathways

• 基因名称：
• UGT8 CGT UGT4

• 蛋白名称：
• CGT

• Human Gene Id：
• 7368

• Human Swiss Prot No：
• Q16880

• 免疫原：
• Synthesized peptide derived from human CGT

• 特异性：
• This antibody detects endogenous levels of human CGT

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:50-200, WB 1:500-2000. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• 2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.45;Ceramide UDP-galactosyltransferase;Cerebroside synthase;UDP-galactose-ceramide galactosyltransferase)

• 实测条带：
• 60kD

• 背景：
• UDP glycosyltransferase 8(UGT8) Homo sapiens The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011],

• 功能：
• catalytic activity:UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.,function:Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.,online information:2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor,pathway:Sphingolipid metabolism; galactosylceramide biosynthesis.,similarity:Belongs to the UDP-glycosyltransferase family.,

• 细胞定位：
• Membrane ; Single-pass membrane protein . Endoplasmic reticulum .

• 组织表达：
• Brain,

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