AFG3L2 Polyclonal Antibody
- 货号:YT6098
- 应用:WB;ELISA
- 种属:Human;Mouse
- 简介:
- >>Spinocerebellar ataxia
- 免疫原:
- Synthesized peptide derived from human AFG3L2. at AA range: 744-793
- 特异性:
- AFG3L2 Polyclonal Antibody detects endogenous levels of AFG3L2
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000, ELISA 1:10000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)
- 背景:
- This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq, Jul 2008],
- 功能:
- cofactor:Binds 1 zinc ion per subunit .,function:Putative ATP-dependent protease.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,tissue specificity:Ubiquitous.,
- 细胞定位:
- Mitochondrion . Mitochondrion inner membrane ; Multi-pass membrane protein .
- 组织表达:
- Ubiquitous. Highly expressed in the cerebellar Purkinje cells.
![](/uploadfiles/PIC/yt6098wb42606.jpg)
- Western Blot analysis of 1,mouse-heart 2,293T cells using primary antibody diluted at 1:500(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)