NUT Polyclonal Antibody

    • 货号:YT6064
    • 应用:WB;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • NUT
      • 基因名称:
      • NUT C15orf55
      • 蛋白名称:
      • NUT
      • Human Swiss Prot No:
      • Q86Y26
      • Mouse Swiss Prot No:
      • Q8BHP2
      • 免疫原:
      • Synthesized peptide derived from human NUT. at AA range: 1082-1131
      • 特异性:
      • This antibody detects endogenous levels of NUT
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000, ELISA 1:10000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • Protein NUT (Nuclear protein in testis)
      • 实测条带:
      • 63kD
      • 背景:
      • disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.,disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.,PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.,similarity:Belongs to the FAM22 family.,subcellular location:Shuttles between nucleus and cytoplasm.,tissue specificity:Specifically expressed in testis.,
      • 功能:
      • disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.,disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.,PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.,similarity:Belongs to the FAM22 family.,subcellular location:Shuttles between nucleus and cytoplasm.,tissue specificity:Specifically expressed in testis.,
      • 细胞定位:
      • Cytoplasm . Nucleus . Shuttles between nucleus and cytoplasm. .
      • 组织表达:
      • Specifically expressed in testis.
      • 产品图片
      • Western Blot analysis of 293T cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)