IL-17F Polyclonal Antibody
- 货号：YT6047
- 应用：IHC;IF;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway;>>Th17 cell differentiation;>>Inflammatory bowel disease
- 蛋白名称：
- Interleukin-17F (IL-17F) (Cytokine ML-1) (Interleukin-24) (IL-24)
- 免疫原：
- Synthetic peptide from human protein at AA range: 81-130
- 特异性：
- The antibody detects endogenous IL-17F
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Interleukin-17F (IL-17F;Cytokine ML-1;Interleukin-24;IL-24)
- 背景：
- The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008],
- 功能：
- function:Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in activated, but not resting, CD4+ T-cells and activated monocytes.,
- 组织表达：
- Expressed in T-helper 1 and T-helper 2 cells, basophils and mast cells.
- Immunohistochemical analysis of paraffin-embedded Human-colon-cancer, antibody was diluted at 1:100
