• 靶点：
• CD70

• 简介：
• >>Cytokine-cytokine receptor interaction

• 基因名称：
• CD70 CD27L CD27LG TNFSF7

• 蛋白名称：
• CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70)

• Human Gene Id：
• 970

• Human Swiss Prot No：
• P32970

• Mouse Gene Id：
• 21948

• Mouse Swiss Prot No：
• O55237

• 免疫原：
• Synthetic peptide from human protein at AA range: 150-193

• 特异性：
• The antibody detects endogenous CD70

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD70 antigen (CD27 ligand;CD27-L;Tumor necrosis factor ligand superfamily member 7;CD antigen CD70)

• 背景：
• The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008],

• 功能：
• function:Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,

• 细胞定位：
• Membrane ; Single-pass type II membrane protein .

• 组织表达：
• B-cell,Kidney,

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