CD80 Polyclonal Antibody

    • 货号:YT6014
    • 应用:IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • CD80
      • 简介:
      • >>Cell adhesion molecules;>>Toll-like receptor signaling pathway;>>Intestinal immune network for IgA production;>>Type I diabetes mellitus;>>Autoimmune thyroid disease;>>Systemic lupus erythematosus;>>Rheumatoid arthritis;>>Allograft rejection;>>Graft-versus-host disease;>>Viral myocarditis
      • 基因名称:
      • CD80 CD28LG CD28LG1 LAB7
      • 蛋白名称:
      • T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)
      • Human Gene Id:
      • 941
      • Human Swiss Prot No:
      • P33681
      • Mouse Swiss Prot No:
      • Q00609
      • 免疫原:
      • Synthetic peptide from human protein at AA range: 100-160
      • 特异性:
      • The antibody detects endogenous CD80
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • T-lymphocyte activation antigen CD80 (Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80)
      • 背景:
      • The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],
      • 功能:
      • function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,
      • 细胞定位:
      • Membrane; Single-pass type I membrane protein.
      • 组织表达:
      • Expressed on activated B-cells, macrophages and dendritic cells.
      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded Human-tonsil, antibody was diluted at 1:100
      • Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:400(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).