ENA-78 Polyclonal Antibody
- 货号：YT5961
- 应用：IHC;IF;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>IL-17 signaling pathway;>>TNF signaling pathway;>>Pertussis;>>Rheumatoid arthritis
- 蛋白名称：
- C-X-C motif chemokine 5 (ENA-78(1-78)) (Epithelial-derived neutrophil-activating protein 78) (Neutrophil-activating peptide ENA-78) (Small-inducible cytokine B5) [Cleaved into: ENA-78(8-78); ENA-78(9-
- 免疫原：
- Synthetic peptide from human protein at AA range: 65-114
- 特异性：
- The antibody detects endogenous ENA-78
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- C-X-C motif chemokine 5 (ENA-78(1-78);Epithelial-derived neutrophil-activating protein 78;Neutrophil-activating peptide ENA-78;Small-inducible cytokine B5) [Cleaved into: ENA-78(8-78);ENA-78(9-78)]
- 背景：
- This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013],
- 功能：
- function:Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.,online information:CXCL5 entry,PTM:N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
- 组织表达：
- Bladder,Epithelium,Kidney,Peripheral blood monocyte,Platelet,
- Immunohistochemical analysis of paraffin-embedded human-pancreas-cancer, antibody was diluted at 1:200
