BMP-9 Polyclonal Antibody
- 货号：YT5956
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse
- 简介：
- >>Cytokine-cytokine receptor interaction
- 蛋白名称：
- Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
- 免疫原：
- Synthetic peptide from human protein at AA range: 371-420
- 特异性：
- The antibody detects endogenous BMP-9
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Growth/differentiation factor 2 (GDF-2;Bone morphogenetic protein 9;BMP-9)
- 背景：
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],
- 功能：
- function:Could be involved in bone formation.,online information:GDF2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,
- 组织表达：
- Detected in blood plasma (at protein level).
- Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200
