CD300b Polyclonal Antibody
- 货号:YT5949
- 应用:IHC;IF;ELISA
- 种属:Human;Mouse
- 基因名称:
- CD300LB CD300B CLM7 CMRF35A2 IREM3 LMIR5 TREM5 UNQ2530/PRO6029
- 蛋白名称:
- CMRF35-like molecule 7 (CLM-7) (CD300 antigen-like family member B) (CMRF35-A2) (Immune receptor expressed on myeloid cells 3) (IREM-3) (Leukocyte mono-Ig-like receptor 5) (Triggering receptor express
- 免疫原:
- Synthetic peptide from human protein at AA range: 61-110
- 特异性:
- The antibody detects endogenous CD300b
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CMRF35-like molecule 7 (CLM-7;CD300 antigen-like family member B;CMRF35-A2;Immune receptor expressed on myeloid cells 3;IREM-3;Leukocyte mono-Ig-like receptor 5;Triggering receptor expressed on myeloid cells 5;TREM-5;CD antigen CD300b)
- 背景:
- CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008],
- 功能:
- function:Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitement of GRB2.,PTM:Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN.,tissue specificity:Expressed exclusively in myeloid lineages.,
- 细胞定位:
- Cell membrane ; Single-pass type I membrane protein .
- 组织表达:
- Expressed exclusively in myeloid lineages.
![](/uploadfiles/PIC/yt5949ihc-human-liver-cancer2.jpg)
- Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200