CD297 Polyclonal Antibody
- 货号:YT5943
- 应用:IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31) (ADP-ribosyltransferase C2 and C3 toxin-like 4) (ARTC4) (Dombrock blood group carrier molecule) (Mono(ADP-ribosyl)transferase 4) (NAD(P)(+)--arginine ADP-ri
- 免疫原:
- Synthetic peptide from human protein at AA range: 181-230
- 特异性:
- The antibody detects endogenous CD297
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Ecto-ADP-ribosyltransferase 4 (EC 2.4.2.31;ADP-ribosyltransferase C2 and C3 toxin-like 4;ARTC4;Dombrock blood group carrier molecule;Mono(ADP-ribosyl)transferase 4;NAD(P)(+)--arginine ADP-ribosyltransferase 4;CD antigen CD297)
- 背景:
- This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008],
- 功能:
- catalytic activity:NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine.,catalytic activity:NADP(+) + protein-L-arginine = nicotinamide + N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine.,online information:Blood group antigen gene mutation database,polymorphism:DO is responsible for the Dombrock blood group system. The molecular basis of the Do(a)/Do(b) blood group antigen is a single variation in position 265; Asn-265 corresponds to Do(a) and Asp-265 to Do(b). It is also responsible for the antigens Gregory [Gy(a)], Holley [Hy] and Joseph [Jo(a)].,similarity:Belongs to the Arg-specific ADP-ribosyltransferase family.,tissue specificity:Expressed in spleen and T-cells.,
- 细胞定位:
- Cell membrane; Lipid-anchor, GPI-anchor.
- 组织表达:
- Expressed in spleen and T-cells.
![](/uploadfiles/PIC/yt5943ihc-human-kidney.jpg)
- Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200