IL-19 Polyclonal Antibody
- 货号：YT5895
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Rat
- 简介：
- >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>JAK-STAT signaling pathway
- 蛋白名称：
- Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1)
- 免疫原：
- Synthetic peptide from human protein at AA range: 51-100
- 特异性：
- The antibody detects endogenous IL-19
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)
- 背景：
- The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],
- 功能：
- function:May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.,similarity:Belongs to the IL-10 family.,
- Western blot analysis of 293T Hela VEC KB mouse-kidney lysate, antibody was diluted at 500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
