Calretinin Polyclonal Antibody
- 货号:YT5741
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 免疫原:
- Synthesized peptide derived from calbindin 2 at AA range: 191-240
- 特异性:
- Calretinin Polyclonal Antibody detects endogenous levels of calbindin 2
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Calretinin (CR;29 kDa calbindin)
- 背景:
- This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
- 功能:
- function:Calretinin is a calcium-binding protein which is abundant in auditory neurons.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 6 EF-hand domains.,tissue specificity:Brain.,
- 细胞定位:
- nucleus,cytoplasm,cytosol,gap junction,neuron projection,terminal bouton,synapse,
- Western blot analysis of 293T lysis using CALB2 antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000