• 靶点：
• Endoglycan

• 基因名称：
• PODXL2

• 蛋白名称：
• Podocalyxin-like protein 2

• Human Gene Id：
• 50512

• Human Swiss Prot No：
• Q9NZ53

• Mouse Swiss Prot No：
• Q8CAE9

• 免疫原：
• Synthesized peptide derived from the Internal region of human Endoglycan.

• 特异性：
• Endoglycan Polyclonal Antibody detects endogenous levels of Endoglycan protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PODXL2;Podocalyxin-like protein 2;Endoglycan

• 实测条带：
• 65kD

• 背景：
• This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012],

• 功能：
• PTM:Glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides.,PTM:Sulfation and sialylated O-linked oligosaccharides are necessary for SELL/L-selectin binding.,similarity:Belongs to the podocalyxin family.,subunit:Homodimer; disulfide-linked. Binds to SELL/L-selectin.,tissue specificity:Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells.,

• 细胞定位：
• Membrane ; Single-pass type I membrane protein .

• 组织表达：
• Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells.

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