GDF-3 Polyclonal Antibody
- 货号:YT5646
- 应用:WB;ELISA
- 种属:Human;Rat;Mouse;
- 简介:
- >>Cytokine-cytokine receptor interaction
- 蛋白名称:
- Growth/differentiation factor 3
- 免疫原:
- Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
- 特异性:
- GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GDF3;Growth/differentiation factor 3;GDF-3
- 背景:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],
- 功能:
- online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,
- 细胞定位:
- Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .
![](/uploadfiles/PIC/yt5646-wb.jpg)
- Western Blot analysis of L929 cells using GDF-3 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
![](/uploadfiles/PIC/yt5646-wb(2).jpg)
- Western Blot analysis of L929 cells using GDF-3 Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
![](/uploadfiles/PIC/yt5646wb42213a932.jpg)
- Western Blot analysis of K562 KB using GDF-3 Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000