• 靶点：
• CD239

• 基因名称：
• BCAM

• 蛋白名称：
• Basal cell adhesion molecule

• Human Gene Id：
• 4059

• Human Swiss Prot No：
• P50895

• Mouse Gene Id：
• 57278

• Mouse Swiss Prot No：
• Q9R069

• Rat Gene Id：
• 78958

• Rat Swiss Prot No：
• Q9ESS6

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human BCAM. AA range:191-240

• 特异性：
• CD239 Polyclonal Antibody detects endogenous levels of CD239 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• BCAM;LU;MSK19;Basal cell adhesion molecule;Auberger B antigen;B-CAM cell surface glycoprotein;F8/G253 antigen;Lutheran antigen;Lutheran blood group glycoprotein;CD239

• 实测条带：
• 78kD

• 背景：
• This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],

• 功能：
• cell adhesion, cell-matrix adhesion, biological adhesion, cell-substrate adhesion,

• 细胞定位：
• Membrane; Single-pass type I membrane protein.

• 组织表达：
• Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

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