• 靶点：
• Nov

• 基因名称：
• NOV

• 蛋白名称：
• Protein NOV homolog

• Human Gene Id：
• 4856

• Human Swiss Prot No：
• P48745

• Mouse Gene Id：
• 18133

• Mouse Swiss Prot No：
• Q64299

• Rat Gene Id：
• 81526

• Rat Swiss Prot No：
• Q9QZQ5

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human NOV. AA range:221-270

• 特异性：
• Nov Polyclonal Antibody detects endogenous levels of Nov protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NOV;CCN3;IGFBP9;NOVH;Protein NOV homolog;NovH;CCN family member 3;Insulin-like growth factor-binding protein 9;IBP-9;IGF-binding protein 9;IGFBP-9;Nephroblastoma-overexpressed gene protein homolog

• 实测条带：
• 39kD

• 背景：
• The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009],

• 功能：
• function:Immediate-early protein likely to play a role in cell growth regulation.,similarity:Belongs to the CCN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 TSP type-1 domain.,similarity:Contains 1 VWFC domain.,subunit:Interacts with FBLN1.,tissue specificity:Increased expression in Wilms tumor of the stromal type.,

• 细胞定位：
• Secreted. Cytoplasm . Cell junction, gap junction . Localizes at the gap junction in presence of GJA1. .

• 组织表达：
• Expressed in endiothelial cells (at protein level) (PubMed:21063504). Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type.

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