• 靶点：
• CD158b2/j

• 简介：
• >>Antigen processing and presentation;>>Natural killer cell mediated cytotoxicity;>>Graft-versus-host disease

• 基因名称：
• KIR2DL3/KIR2DS2

• 蛋白名称：
• Killer cell immunoglobulin-like receptor 2DL3/Killer cell immunoglobulin-like receptor 2DS2

• Human Gene Id：
• 3804/100132285

• Human Swiss Prot No：
• P43628/P43631

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human KIR2DL3/KIR2DS2. AA range:131-180

• 特异性：
• CD158b2/j Polyclonal Antibody detects endogenous levels of CD158b2/j protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• KIR2DL3;CD158B2;KIRCL23;NKAT2;Killer cell immunoglobulin-like receptor 2DL3;CD158 antigen-like family member B2;KIR-023GB;Killer inhibitory receptor cl 2-3;MHC class I NK cell receptor;NKAT2a;NKAT2bNatural killer-associated transcript 2;NKAT-2;p58 natural killer cell receptor clone CL-6;p58 NK receptor CL-6;p58.2 MHC class-I-specific NK receptor;CD158b2;KIR2DS2;CD158J;NKAT5;Killer cell immunoglobulin-like receptor 2DS2;

• 实测条带：
• 38kD

• 背景：
• Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

• 功能：
• function:Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,

• 细胞定位：
• Cell membrane; Single-pass type I membrane protein.

• 组织表达：
• Blood,Natural kille

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs