CD163b Polyclonal Antibody
- 货号:YT5406
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- Scavenger receptor cysteine-rich type 1 protein M160
- 免疫原:
- The antiserum was produced against synthesized peptide derived from the Internal region of human CD163L1. AA range:391-440
- 特异性:
- CD163b Polyclonal Antibody detects endogenous levels of CD163b protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CD163L1;CD163B;M160;Scavenger receptor cysteine-rich type 1 protein M160;CD163 antigen-like 1;CD163b
- 背景:
- This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
- 功能:
- similarity:Contains 12 SRCR domains.,tissue specificity:Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.,
- 细胞定位:
- [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Secreted .
- 组织表达:
- Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.
![](/uploadfiles/PIC/yt5406-wb.jpg)
- Western Blot analysis of HeLa cells using CD163b Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
![](/uploadfiles/PIC/yt5406ihchuman-lung(2).jpg)
- Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
![](/uploadfiles/PIC/yt5406_pic802718522.jpg)
- Western blot analysis of lysate from HeLa cells, using CD163L1 Antibody.