• 靶点：
• CD163b

• 基因名称：
• CD163L1

• 蛋白名称：
• Scavenger receptor cysteine-rich type 1 protein M160

• Human Gene Id：
• 283316

• Human Swiss Prot No：
• Q9NR16

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human CD163L1. AA range:391-440

• 特异性：
• CD163b Polyclonal Antibody detects endogenous levels of CD163b protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD163L1;CD163B;M160;Scavenger receptor cysteine-rich type 1 protein M160;CD163 antigen-like 1;CD163b

• 实测条带：
• 160kD

• 背景：
• This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino acid SRCR domain, which may mediate protein-protein interaction and ligand binding. The encoded protein contains twelve SRCR domains, a transmembrane region and a cytoplasmic domain. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],

• 功能：
• similarity:Contains 12 SRCR domains.,tissue specificity:Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.,

• 细胞定位：
• [Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Secreted .

• 组织表达：
• Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and macrophage cell lines. Isoform 2 is only expressed in spleen.

Comprehensive pan-cancer analysis reveals EPHB2 is a novel predictive biomarker for prognosis and immunotherapy response BMC CANCER Xu Shengshan IF Human 1:1000 lung adenocarcinoma (LUAD) tissue
货号：YT5406

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