• 靶点：
• Glut5

• 简介：
• >>Carbohydrate digestion and absorption

• 基因名称：
• SLC2A5

• 蛋白名称：
• Solute carrier family 2 facilitated glucose transporter member 5

• Human Gene Id：
• 6518

• Human Swiss Prot No：
• P22732

• Mouse Swiss Prot No：
• Q9WV38

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A5. AA range:31-80

• 特异性：
• Glut5 Polyclonal Antibody detects endogenous levels of Glut5 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SLC2A5;GLUT5;Solute carrier family 2, facilitated glucose transporter member 5;Fructose transporter;Glucose transporter type 5, small intestine;GLUT-5

• 实测条带：
• 55kD

• 背景：
• The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016],

• 功能：
• function:Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.,induction:By forskolin (in Caco-2 cells).,mass spectrometry: PubMed:11840567,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,tissue specificity:Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.,

• 细胞定位：
• Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A. .

• 组织表达：
• Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.

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