• 靶点：
• CD58

• 简介：
• >>Cell adhesion molecules;>>Epstein-Barr virus infection

• 基因名称：
• CD58

• 蛋白名称：
• Lymphocyte function-associated antigen 3

• Human Gene Id：
• 965

• Human Swiss Prot No：
• P19256

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human CD58. AA range:31-80

• 特异性：
• CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD58;LFA3;Lymphocyte function-associated antigen 3;Ag3;Surface glycoprotein LFA-3;CD58

• 实测条带：
• 27kD

• 背景：
• This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],

• 功能：
• function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,

• 细胞定位：
• [Isoform 1]: Cell membrane; Single-pass type I membrane protein.

• 组织表达：
• Brain,Erythrocyte,

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