• 靶点：
• CD2

• 简介：
• >>Cell adhesion molecules;>>Hematopoietic cell lineage

• 基因名称：
• CD2

• 蛋白名称：
• T-cell surface antigen CD2

• Human Gene Id：
• 914

• Human Swiss Prot No：
• P06729

• Mouse Swiss Prot No：
• P08920

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the N-terminal region of human CD2. AA range:31-80

• 特异性：
• CD2 Polyclonal Antibody detects endogenous levels of CD2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD2;SRBC;T-cell surface antigen CD2;Erythrocyte receptor;LFA-2;LFA-3 receptor;Rosette receptor;T-cell surface antigen T11/Leu-5;CD2

• 实测条带：
• 39kD

• 背景：
• The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016],

• 功能：
• function:CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.,online information:CD2 entry,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD2AP (By similarity). Interacts with PSTPIP1.,

• 细胞定位：
• Cell membrane ; Single-pass type I membrane protein .

• 组织表达：
• Expressed in natural killer cells (at protein level).

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