• 靶点：
• DCI

• 简介：
• >>Fatty acid degradation

• 基因名称：
• ECI1

• 蛋白名称：
• Enoyl-CoA delta isomerase 1 mitochondrial

• Human Gene Id：
• 1632

• Human Swiss Prot No：
• P42126

• Mouse Swiss Prot No：
• P42125

• 免疫原：
• Synthesized peptide derived from DCI . at AA range: c-terminal

• 特异性：
• DCI Polyclonal Antibody detects endogenous levels of DCI protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• ECI1;DCI;Enoyl-CoA delta isomerase 1, mitochondrial;3,2-trans-enoyl-CoA isomerase;Delta(3),Delta(2)-enoyl-CoA isomerase;D3,D2-enoyl-CoA isomerase;Dodecenoyl-CoA isomerase

• 实测条带：
• 30kD

• 背景：
• This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010],

• 功能：
• catalytic activity:(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.,function:Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the enoyl-CoA hydratase/isomerase family.,subunit:Homotrimer.,

• 细胞定位：
• Mitochondrion matrix .

• 组织表达：
• Expressed in liver (at protein level).

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