Kallistatin Polyclonal Antibody
- 货号：YT5216
- 应用：WB;IHC;IF;ELISA
- 种属：Human
- 免疫原：
- The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210
- 特异性：
- Kallistatin Polyclonal Antibody detects endogenous levels of Kallistatin protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SERPINA4;KST;PI4;Kallistatin;Kallikrein inhibitor;Peptidase inhibitor 4;PI-4;Serpin A4
- 背景：
- function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
- 功能：
- function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma.,
- 组织表达：
- Expressed by the liver and secreted in plasma.
- Western Blot analysis of K562 cells using Kallistatin Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
- Western blot analysis of lysate from K562 cells, using SERPINA4 Antibody.
