• 靶点：
• FGF-20

• 简介：
• >>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>PI3K-Akt signaling pathway;>>Regulation of actin cytoskeleton;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Melanoma;>>Breast cancer;>>Gastric cancer

• 基因名称：
• FGF20

• 蛋白名称：
• Fibroblast growth factor 20

• Human Gene Id：
• 26281

• Human Swiss Prot No：
• Q9NP95

• Mouse Gene Id：
• 80857

• Mouse Swiss Prot No：
• Q9ESL9

• Rat Gene Id：
• 66017

• Rat Swiss Prot No：
• Q9EST9

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human FGF20. AA range:151-200

• 特异性：
• FGF-20 Polyclonal Antibody detects endogenous levels of FGF-20 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• FGF20;Fibroblast growth factor 20;FGF-20

• 实测条带：
• 23kD

• 背景：
• The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009],

• 功能：
• function:Neurotrophic factor that regulates central nervous development and function.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Predominantly expressed in the cerebellum.,

• 细胞定位：
• Secreted .

• 组织表达：
• Predominantly expressed in the cerebellum.

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